Staff profile

Dr Laurice Fretwell

Course Director in Human Sciences

Laurice Fretwell in a teaching room


College of Life and Natural Sciences


School of Human Sciences

Research centre

Human Sciences Research Centre


Kedleston Road, Derby Campus



As Course Director for the School of Human Sciences, I work across all disciplines to enhance teaching, learning and the student experience.    

My background is in Physiology and Pharmacology and I continue to teach and research in these areas.

Teaching responsibilities

I am module leader for our Industrial Placement Year modules, and teach on different modules on Human Biology and Biomedical Health.  I also supervise undergraduate and postgraduate student research projects.

Professional interests

I lead on the enhancement and embedding of employaility activity across the School of Human Sciences.  As part of this, I am always interested to speak to employers about how we can work together to provide work experience or volunteering for our students, and ensure that we produce highly-skilled workplace-ready graduates.  

Research interests

After graduating from BSc (Hons.) Physiology and Pharmacology, I completed my PhD at Nottingham Trent University into the role of BKCa channels in adenosine-receptor mediated cytoprotection (using H9c2 cells and ventricle strips to model hypoxia-reoxygenation injury).  

I was then awarded a Career Development Fellowship in Cardiovascular Pharmacology & Drug Discovery at the University of Nottingham, where I monitored regional haemodynamic responses in vivo and developed skills in pressure myography.  

Since then, I have supervised PhD and MRes students and am keen to pursue research and collaborate in the following areas:

Membership of professional bodies

Fellow of the Higher Education Authority


BSc (Hons.) Physiology and Pharmacology, Nottingham Trent University

PhD: The role of BKCa channels in adenosine receptor-mediated cytoprotection, Nottingham Trent University

Recent publications

Driskel M, Horsley A, Fretwell LClayton N, Al-Aloul M. (2019) Lung clearance index in detection of post-transplant bronchiolitis obliterans syndrome. ERJ Open Res. 5: 00164-2019.

Carter JJ, Fretwell LV, Woolard J. (2017) Effects of 4 multitargeted receptor tyrosine kinase inhibitors on regional hemodynamics in conscious, freely moving rats. FASEB J. 31(3):1193-1203. 

Fretwell LV, Woolard J. (2013) Cardiovascular responses to retigabine in conscious rats--under normotensive and hypertensive conditions. Br J Pharmacol. 169(6):1279-89. 

Baker JG, Kemp P, March J, Fretwell L, Hill SJ, Gardiner SM. (2011) Predicting in vivo cardiovascular properties of β-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses. FASEB J. 25(12):4486-97. 

Fretwell L, Dickenson JM. (2011) Role of large-conductance Ca²+-activated K+ channels in adenosine A₁ receptor-mediated pharmacological postconditioning in H9c2 cells. Can J Physiol Pharmacol. 89(1):24-30. 

Fretwell L, Dickenson JM. (2009) Role of large-conductance Ca(2+) -activated potassium channels in adenosine A(1) receptor-mediated pharmacological preconditioning in H9c2 cells. Eur J Pharmacol. 618(1-3):37-44.